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. 2010 Jun 9;133(7):2032–2044. doi: 10.1093/brain/awq132

Figure 3.

Figure 3

α-Synuclein and SNARE proteins co-localize in the striatum of α-syn(1-120) mice. Confocal imaging shows that aggregates containing truncated α-synuclein (A) and SNAP-25 (B) co-localize (C). The distribution of mouse α-synuclein (D) and SNAP-25 (E) is homogeneous (F) in control mice. Confocal imaging shows co-localization (I) of accumulated syntaxin-1 (G) and SNAP-25 (H). Note the homogeneous distribution of syntaxin-1 (J) and SNAP-25 (K) in control mice. Dopamine transporter (DAT) (M) and SNAP-25 (N) co-localize (O). Dopamine transporter and SNAP-25 staining differs between transgenic and C57BL/6S control mice (P–R). Bar = 20 µm (A–F), 10 µm (G–L).