Table 1.
Baseline characteristics of our study sample.
| Women (n=2018) | Men (n=1760) | |
|---|---|---|
| Age, years | 40±9 | 40±9 |
| Systolic BP, mm Hg | 113±14 | 121±12 |
| Diastolic BP, mm Hg | 73±9 | 78±9 |
| Hypertension, % | 12 | 20 |
| Poorly controlled Hypertension, % | 2.0 | 2.8 |
| Well controlled Hypertension, % | 5.3 | 6.2 |
| BMI, kg/m2 | 25.9±6.0 | 27.9±4.7 |
| Waist circumference, cm | 86.9±15.3 | 95.5±12.5 |
| Obesity, % | 20 | 25 |
| Abdominal obesity, % | 40 | 34 |
| Current smoker, % | 14 | 16 |
| Alcohol consumption, ounces per week |
3 (0,8) | 8 (2,19) |
| eGFR, ml/min/1.73m2 | 99±32 | 100±17 |
| Glucose, mg/dL | 92±18 | 98±16 |
| Diabetes, % | 2.3 | 3.0 |
| Insulin-dependent Diabetes (% of participants with diabetes) |
23 | 10 |
| UACR, mg/g | 4.7 (3.1,8.9) | 3.2 (2.2,5.8) |
| Total cholesterol, mg/dL | 185±34 | 193±37 |
| LDL cholesterol, mg/dL | 105±30 | 120±32 |
| HDL cholesterol, mg/dL | 61±16 | 47±12 |
| Triglycerides, mg/dL | 80 (59,114) | 107 (72,161) |
| Metabolic Syndrome, % | 15 | 28 |
| Dyslipidemia, % | 29 | 40 |
| Family history of CVD, % | 33 | 33 |
| Angiopoietin-2, ng/mL | 2.03 (1.51,2.72) | 1.71 (1.34,2.23)) |
| Log-Angiopoietin-2, ng/mL | 0.71 (0.41,1.00) | 0.54 (0.29,0.80) |
| Soluble Tie-2, ng/mL | 14.35 (12.02,17.42) | 15.02 (12.71,18.29) |
| Log-sTie-2, ng/mL | 2.71 (2.54,2.91) | 2.66 (2.49,2.86) |
BP, blood pressure; HDL, high-density lipoprotein; eGFR, estimated glomerular filtration rate, BMI, body mass index; eGFR, estimates glomerular filtration rate; UACR, urinary albumin/creatinine ratio; LDL, low-density lipoprotein; HDL, high-density lipoprotein; . Data are mean±standard deviation for continuous traits (except for triglycerides, Angiopoietin-2, Tie-2 and alcohol consumption where median (quartile1, quartile3) are provided) and percentages for categorical data.
Definitions: poorly controlled hypertension: participants on antihypertensive medication, but with systolic BP ≥140 or diastolic BP ≥ 90 mmHg; well controlled hypertension: participants on antihypertensive medication and with a systolic BP <140 and a diastolic BP <90 mmHg; obesity: body mass index ≥ 30 kg/m2); abdominal obesity: waist circumference ≥ 89 cm in women and ≥ 102 cm in men; dyslipidemia: total cholesterol > 200 mg/dL; smoking: smoking at least on cigarette per day in the year preceding the examination.