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Pretreatment with WIN-51,708 (5 mg/kg, i.p.) attenuates METH-induced apoptosis in the striatum. METH was injected i.p. at a dose of 30 mg/kg. Apoptosis was assessed at 24 h post-METH by TUNEL. SEM, standard error of the mean values. *P < 0.05 compared to METH.
