Table 4.
Number and diameter of TH and ChAT varicosities within or outside microproximity in the mPFC of rats.
| Infralimbic Ctx | Prelimbic Ctx | Cingulate Ctx | |
|---|---|---|---|
| LAYER II/III | |||
| TH varicosities within | 0.52 ± 0.03† | 0.53 ± 0.04†* | 0.50 ± 0.04† |
| microproximity | (666 ± 28) | (689 ± 44†*) | (656 ± 44) |
| TH varicosities outside | 0.26 ± 0.03†‡§ | 0.33 ± 0.04†*‡§ | 0.31 ± 0.04†§ |
| microproximity | (672 ± 62‡§) | (608 ± 37†§) | (601 ± 12‡§) |
| ChAT varicosities | 0.53 ± 0.01† | 0.59 ± 0.03†* | 0.54 ± 0.04† |
| within microproximity | (664 ± 45§) | (641 ± 09†*§) | (641 ± 23) |
| ChAT varicosities outside | 0.38 ± 0.13† | 0.38 ± 0.02†*§ | 0.35 ± 0.03†§ |
| microproximity | (654 ± 29§) | (620 ± 12†§) | (626 ± 24) |
| LAYER V | |||
| TH varicosities within | 0.49 ± 0.06† | 0.56 ± 0.02† | 0.53 ± 0.03†* |
| microproximity | (688 ± 75) | (717 ± 36) | (649 ± 16†) |
| TH varicosities outside | 0.33 ± 0.02†‡§ | 0.39 ± 0.04†*‡§ | 0.37 ± 0.05†‡§ |
| microproximity | (639 ± 44‡§) | (697 ± 40‡§) | (627 ± 13‡†§) |
| ChAT varicosities within | 0.57 ± 0.05†‡ | 0.61 ± 0.04†‡ | 0.59 ± 0.02†* |
| microproximity | (665 ± 21†§) | (704 ± 35§) | (671 ± 19) |
| ChAT varicosities outside | 0.36 ± 0.02† | 0.49 ± 0.06†*§ | 0.42 ± 0.03†§ |
| microproximity | (627 ± 28‡†§) | (690 ± 42‡§) | (657 ± 26) |
All values are means ± SEM expressed in number of varicosities/μm or (diameter) expressed in nm from six animals. Abbreviations: ChAT, choline acetyltransferase; Ctx, cortex; TH, tyrosine hydroxylase.
*Paired student t test, p < 0.05, two-tailed, ChAT vs TH varicosities.
†Paired student t test, p < 0.05, two-tailed, within compared outside microproximity.
‡One-Way Anova, p < 0.05, two-tailed, Region-specific difference.
§Paired student t test, p < 0.05, two-tailed, Layer-specific difference.