Table 2.
Regions in which older adults exhibit more fMRI task-related activation than young adults (uncorrected p = 0.001, whole brain analysis).
| Anatomical location | BA | Cluster size | Coordinates of peaks | z score |
|---|---|---|---|---|
| FRONTAL AREAS | ||||
| L Superior frontal gyrus | 9 | 79 | −38 42 30 | 3.9 |
| L Middle frontal gyrus | 8 | −36 34 40 | 3.38 | |
| L Precentral gyrus | 6 | 23 | −40 −12 42 | 3.62 |
| R Medial frontal gyrus | 9 | 25 | 16 38 30 | 3.58 |
| R Middle frontal gyrus | 10 | 27 | 38 50 22 | 3.36 |
| R Middle frontal gyrus | 46 | 39 | 46 26 26 | 3.34 |
| L Inferior frontal gyrus | 44 | 36 | −36 10 28 | 3.31 |
| L Middle frontal gyrus | 9 | −30 10 34 | 3.15 | |
| TEMPORAL AREAS | ||||
| R Middle temporal gyrus | 21 | 136 | 42 0 −22 | 3.85 |
| PARIETAL AREAS | ||||
| R Precuneus | 7 | 805 | 12 −56 46 | 4.54 |
| L Precuneus | 7 | −2 −50 52 | 3.99 | |
| R Precuneus | 7 | 12 −48 44 | 3.97 | |
| R Cuneus | 19 | 20 −84 34 | 3.37 | |
| R Postcentral gyrus | 1 | 34 | 40 −20 46 | 3.31 |
| R Postcentral gyrus | 3 | 50 −12 44 | 3.22 | |
| R Fusiform gyrus | 37 | 10 | 34 −44 −14 | 3.45 |
| SUBCORTICAL AREAS | ||||
| L Cerebellum (HIII) | 70 | −12 −34 −22 | 4.59 | |
| L Cerebellum (Crus I) | 59 | 30 −70 −30 | 3.97 | |
| L Cerebellum (Crus I) | 15 | −22 −72 −36 | 3.4 |
BA, Brodmann's area; L, left; R, right.