Skip to main content
. Author manuscript; available in PMC: 2010 Jun 28.
Published in final edited form as: Clin Trials. 2009 Jun;6(3):272–287. doi: 10.1177/1740774509105380

Figure 3.

Figure 3

Comparison of treatments for BIG 1-98 monotherapy cohorts with respect to DFS. Hazard ratios and 95% confidence intervals are estimated from a Cox proportional hazards model. The locations of the squares indicate the estimated hazard ratio of a DFS event for letrozole vs tamoxifen, and the size of the squares is proportional to the statistical information available for each comparison. The solid vertical line indicates the overall treatment effect estimate of HR = 0.82, and the dashed vertical line shows the location of the null hypothesis of no treatment difference