Table 2.
Predictive value of temporary renal dysfunction on long-term CKD, using various (small) changes in CKD-EPI eGFR
| Cutoff Values | No Change | Temporary Decline | Persistent Decline |
|---|---|---|---|
| 10% | |||
| patients (n [%]) | 815 (62) | 261 (20) | 232 (18) |
| RR (95% CI) | Reference | 3.4 (2.7 to 4.1) | 3.6 (2.8 to 4.4) |
| 20% | |||
| patients (n [%]) | 856 (65) | 313 (24) | 139 (11) |
| RR (95% CI) | Reference | 3.5 (2.8 to 4.2) | 4.2 (3.2 to 5.2) |
| 30% | |||
| patients (n [%]) | 863 (66) | 337 (26) | 108 (8) |
| RR (95% CI) | Reference | 3.5 (2.8 to 4.2) | 4.3 (3.3 to 5.4) |
| 40% | |||
| patients (n [%]) | 866 (66) | 355 (27) | 87 (7) |
| RR (95% CI) | Reference | 3.6 (2.9 to 4.3) | 3.9 (2.8 to 5.1) |
| 50% | |||
| patients (n [%]) | 866 (66) | 365 (28) | 77 (6) |
| RR (95% CI) | Reference | 3.8 (2.9 to 4.3) | 3.9 (2.8 to 5.1) |
Adjustment for demographics (age, gender), cerebrovascular history, cardiovascular risk factors (polyvascular disease, smoking, hypertension, diabetes, hypercholesterolemia, heart failure, chronic obstructive pulmonary disease), baseline CKD-EPI eGFR, and BP-lowering drugs (diuretics, angiotensin-converting enzyme inhibitors, calcium antagonists, and angiotensin receptor blockers).