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. 2010 May 23;10:229. doi: 10.1186/1471-2407-10-229

Table 1.

IC50 values for doxorubicin and paclitaxel

IC50
Drug AA8 EmtR1 MCF-7 MCF-7/Mx MDA-MB-231 MDA-MB-231/Dox
Doxorubicin (μM) 0.6 48.4 0.5 30.5 0.04 2.2
Paclitaxel (μM) 0.1 65.3 0.09 9.9 0.005 0.829

Drug concentrations inhibiting cell growth by 50% (IC50) were calculated from relative survival curves (see Figure 2) using the median-effect principle [16].