Table 4.
Association statistics for CCR2-V64I genotype for high risk HPV infection in the control group
| High risk HPV positive (201) | High risk HPV negative (1053) | |||||
|---|---|---|---|---|---|---|
| Black 62 (31) | Mixed-ancestry 139 (69) | Black 212 (20) | Mixed-ancestry 841 (80) | Genotype-high risk HPV association, adjusted for ethnicity and smoking | ||
| Genotypes | n (%) | n (%) | n (%) | n (%) | P-value | OR (95% CI) |
| CCR2 G→A | ||||||
| GG | 34 (55) | 94 (68) | 135 (64) | 546 (65) | - | 1 |
| AG | 27 (43) | 41 (29) | 74 (35) | 286 (34) | 0.904 | 0.98 (0.71-1.35) |
| AA | 1 (2) | 4 (3) | 3 (1) | 9 (1) | 0.163 | 2.14 (0.73-6.25) |
| AG + AA | 28 (45) | 45 (32) | 77 (36) | 295 (35) | 0.913 | 1.02 (0.74-1.40) |
High risk HPV positive = Positive for Hybrid Capture II HPV Test, High risk HPV negative = Negative for Hybrid Capture II HPV Test.