Table 5.
Association statistics for CCR2-V64I genotypes for HSIL in the control group
| Normal cytology (n = 1070) | HSIL positive (n = 45) | |||||
|---|---|---|---|---|---|---|
| Black 210 (20) | Mixed-ancestry 860 (80) | Black 16 (36) | Mixed-ancestry 29 (64) | Genotype-HSIL association, adjusted for ethnicity and smoking | ||
| Genotypes | n (%) | n (%) | n (%) | n (%) | P-value | OR (95% CI) |
| CCR2 G→A | ||||||
| GG | 124 (59) | 563 (66) | 12 (75) | 21 (72) | - | 1 |
| AG | 84 (40) | 287 (33) | 4 (25) | 8 (28) | 0.190 | 0.64 (0.32-1.25) |
| AA | 2 (1) | 10 (1) | 0 (0) | 0 (0) | - | - |
| AG + AA | 86 (41) | 297 (35) | 4 (30) | 8 (28) | 0.157 | 0.61 (0.31-1.21) |
HSIL positive = Positive for HSIL by pap smear test, Normal cytology = Negative for pap smear test.