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. 2010 Jun 28;5(6):e11082. doi: 10.1371/journal.pone.0011082

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Dickson et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The top 50 highest Zp, , and Zpx values were plotted on the 2-D map of the original cd00300 alignment (top) which contains systematic misalignments and the repaired version of cd00300 (bottom) with many misalignments removed. The data is displayed as a predicted contact map where black-filled circles are pairs in contact and white-filled circles are pairs not in contact. The majority of high-scoring Zp pairs in the original alignment are uninformative local contacts located in a major region of misalignment (top left). The contact maps of and Zpx cover much more of secondary and tertiary structure in both the original and repaired alignments.

Inline graphic — The top 50 highest Zp, , and Zpx values were plotted on the 2-D map of the original cd00300 alignment (top) which contains systematic misalignments and the repaired version of cd00300 (bottom) with many misalignments removed. The data is displayed as a predicted contact map where black-filled circles are pairs in contact and white-filled circles are pairs not in contact. The majority of high-scoring Zp pairs in the original alignment are uninformative local contacts located in a major region of misalignment (top left). The contact maps of and Zpx cover much more of secondary and tertiary structure in both the original and repaired alignments.