Figure 3. Unsupervised analysis of epicardial gene expression post infarction.

A) Self- organizing maps were used to derive six clusters two of which, (3 and 4) contain genes that are strongly regulated. Cluster 3, includes epicardial signature genes whose expression decreases sharply in the epicardium but remains low in muscle post-infarction. Cluster 4 contains epicardial signature genes that are largely unchanged in the epicardium but are increased in muscle post-infarction. B) Heat map of data in A).