Table 1. Epicardial Genes.
Fold difference | Gene Bank accesion | Gene Symbol | Gene Description |
269.6 | BQ084786 | Upk3b | uroplakin 3B |
199.4 | BB348674 | Gpm6a | glycoprotein m6a |
129.8 | BI452905 | Dmkn | dermokine |
88.97 | AV290571 | C2 | complement component 2 (within H-2S) |
81.48 | BB427704 | Upk1b | uroplakin 1B |
76.86 | NM_026228 | Slc39a8 | solute carrier family 39 (metal ion transporter), member 8 |
68.68 | AK004699 | Cyp2s1 | cytochrome P450, family 2, subfamily s, polypeptide 1 |
56.12 | BB118542 | Slc26a3 | solute carrier family 26, member 3 |
53.11 | BB325766 | Lrrn4 | leucine rich repeat neuronal 4 |
45.18 | NM_031170 | Krt8 | keratin 8 |
45.14 | NM_011315 | Saa3 | serum amyloid A 3 |
42.83 | NM_008471 | Krt19 | keratin 19 |
37.65 | AW556821 | 2610018G03Rik | RIKEN cDNA 2610018G03 gene |
36.93 | NM_013473 | Anxa8 | annexin A8 |
35.12 | K02782 | C3 | complement component 3 |
33.93 | AJ132433 | Prr15 | proline rich 15 |
33.63 | BB805362 | Slc9a3r1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 |
31.76 | BC005611 | Chi3l1 | chitinase 3-like 1 |
31.32 | BB392676 | 1500015O10Rik | RIKEN cDNA 1500015O10 gene |
30.71 | U88064 | Bnc1 | basonuclin 1 |
29.94 | AK003577 | Muc16 | mucin 16 |
28.49 | NM_008344 | Igfbp6 | insulin-like growth factor binding protein 6 |
28.24 | BC023060 | Efemp1 | epidermal growth factor-containing fibulin-like extracellular matrix protein 1 |
26.95 | NM_021426 | Nkain4 | Na+/K+ transporting ATPase interacting 4 |
26.57 | BC015076 | Mpzl2 | myelin protein zero-like 2 |
26.08 | AI852300 | Ildr2 | immunoglobulin-like domain containing receptor 2 |
… | … | … | … |
8.79 | NM_00902 | Aldh1a2 | Aldehyde dehydrogenase family 1 |
5.15 | AK012980 | Tbx18 | T-box18 |
List of epicardial genes expressed in epicardial samples isolated by LCM as described in Materials and Methods. Genes from Cluster 1 (from Figure 1), were selected for statistically significant upregulation in the epicardial samples, a normalized >4-fold increased expression in the epicardial sample compared to the muscle control and raw expression of at least 20 in the epicardial samples. This selection identified 197 unique epicardial signature genes. This Table includes top hits with a cut off at 25 fold induction in epicardial samples plus two selected epicardial genes with lower induction.