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. 2010 Jun 28;5(6):e11429. doi: 10.1371/journal.pone.0011429

Table 1. Epicardial Genes.

Fold difference Gene Bank accesion Gene Symbol Gene Description
269.6 BQ084786 Upk3b uroplakin 3B
199.4 BB348674 Gpm6a glycoprotein m6a
129.8 BI452905 Dmkn dermokine
88.97 AV290571 C2 complement component 2 (within H-2S)
81.48 BB427704 Upk1b uroplakin 1B
76.86 NM_026228 Slc39a8 solute carrier family 39 (metal ion transporter), member 8
68.68 AK004699 Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1
56.12 BB118542 Slc26a3 solute carrier family 26, member 3
53.11 BB325766 Lrrn4 leucine rich repeat neuronal 4
45.18 NM_031170 Krt8 keratin 8
45.14 NM_011315 Saa3 serum amyloid A 3
42.83 NM_008471 Krt19 keratin 19
37.65 AW556821 2610018G03Rik RIKEN cDNA 2610018G03 gene
36.93 NM_013473 Anxa8 annexin A8
35.12 K02782 C3 complement component 3
33.93 AJ132433 Prr15 proline rich 15
33.63 BB805362 Slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
31.76 BC005611 Chi3l1 chitinase 3-like 1
31.32 BB392676 1500015O10Rik RIKEN cDNA 1500015O10 gene
30.71 U88064 Bnc1 basonuclin 1
29.94 AK003577 Muc16 mucin 16
28.49 NM_008344 Igfbp6 insulin-like growth factor binding protein 6
28.24 BC023060 Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1
26.95 NM_021426 Nkain4 Na+/K+ transporting ATPase interacting 4
26.57 BC015076 Mpzl2 myelin protein zero-like 2
26.08 AI852300 Ildr2 immunoglobulin-like domain containing receptor 2
8.79 NM_00902 Aldh1a2 Aldehyde dehydrogenase family 1
5.15 AK012980 Tbx18 T-box18

List of epicardial genes expressed in epicardial samples isolated by LCM as described in Materials and Methods. Genes from Cluster 1 (from Figure 1), were selected for statistically significant upregulation in the epicardial samples, a normalized >4-fold increased expression in the epicardial sample compared to the muscle control and raw expression of at least 20 in the epicardial samples. This selection identified 197 unique epicardial signature genes. This Table includes top hits with a cut off at 25 fold induction in epicardial samples plus two selected epicardial genes with lower induction.