Table 1.

Heart characteristics.

Genotype	+/+	−/−
Heart weight (mg)	107.0±5.5	116.6±12.0
Heart weight/body weight (mg/g)	4.2±0.1	4.3±0.2
LV end diastolic diameter (mm)	2.52±0.09	3.36±0.07**
LV end systolic diameter (mm)	0.88±0.1	1.28±0.06*
Fractional shortening	0.65±0.03	0.59±0.02
Heart rate (min–1)	724±19	627±16*
LV anterior wall thickness (mm)	0.86±0.03	0.90±0.02
LV posterior wall thickness (mm)	0.88±0.04	0.94±0.01
AMP/ATP-ratio (basal conditions)	0.06±0.01	0.13±0.03*
AMP/AT- ratio (ischemic conditions)	0.11±0.03	0.30±0.07*
Glycogen (nmol glucose/g (wet weight)	15.0±1.14	13.3±1.1
Citrate synthase activity (A.U.)	100.0±4.5	93.0±4.7
Cytochrome C expression (A.U.)	100.0±7.3	91.9±6.2
ATP synthase expression (A.U.)	100.0±6.2	97.3±7.5

Values are mean±SEM, n=5–12,

^*P<0.05 and

^**P<0.01 vs. control