Table 3.
Post ischemic functional recovery in the aerobically perfused ex vivo working mouse heart after 20 min of ischemia.
Genotype | +/+ | −/− |
---|---|---|
Heart Rate (beats • min−1) | 204 ± 11 | 177 ± 15 |
Rate pressure product (bpm • mmHg • 10−3) | 12 ± 1.0 | 7 ± 1.3* |
Cardiac Work (ml • mmHg • min−1) | 2.0 ± 0.4 | 0.5 ± 0.4** |
Cardiac Output (ml/min) | 3.3 ± 0.7 | 0.9 ± 0.6* |
Aortic Output (ml/min) | 1.8 ± 0.5 | 0.4 ± 0.3 |
Cardiac Power (mjoules • min-1) | 31.2 ± 6.7 | 5.5 ± 3.9* |
Values are mean ± SEM, n = 7–17,
P <0.05 vs. control,
P <0.01