Table 2. Mutants with defects in infectivity but not in morphogenesis or proliferation.
Gene names and proven or predicted protein functions are presented for mutants that exhibited defects in infectivity (as defined in text) but not in colony morphology (M scores were 1 or less) or proliferation (DTMUTANT < DTWT + 2 s.d.).
| Disrupted gene | Function of protein product |
|---|---|
| orf19.3384 | Cell wall component: protein |
| orf19.529 | Cell wall component: protein |
| PGA32/orf19.6784 | Cell wall component: protein |
| CHS4/orf19.7349 | Cell wall composition: carbohydrate |
| CHS7/orf19.2444 | Cell wall composition: carbohydrate |
| CHT2/orf19.3895 | Cell wall composition: carbohydrate |
| orf19.753 | Cell wall composition: carbohydrate |
| DUN1/orf19.4002 | DNA damage response |
| ESC4/orf19.1445 | DNA damage response |
| CRZ1/orf19.7359 | Gene expression: transcription factor |
| MTLA1/orf19.3201 | Gene expression: transcription factor |
| orf19.2315 | Gene expression: transcription factor |
| orf19.7397 | Gene expression: transcription factor |
| SEF1/orf19.3753 | Gene expression: transcription factor |
| orf19.2961 | Gene expression: transcription factor |
| CYB1/orf19.7049 | Lipid biosynthesis and regulation |
| HET1/orf19.6327 | Lipid biosynthesis and regulation |
| orf19.3283 | Lipid biosynthesis and regulation |
| orf19.4831 | Lipid biosynthesis and regulation |
| orf19.6411 | Lipid biosynthesis and regulation |
| MID1/orf19.3212 | Metal ion homeostasis: calcium |
| CFL2/orf19.1264 | Metal ion homeostasis: iron |
| HAK1/orf19.6249 | Metal ion homeostasis: potassium |
| orf19.3290 | Miscellaneous: aerobic respiration |
| CDC10/orf19.548 | Miscellaneous: cell cycle |
| NMD5/orf19.4188 | Miscellaneous: nuclear import of proteins |
| orf19.1392 | Miscellaneous: protein folding |
| CDC19/orf19.3575 | Nutrient acquisition and metabolism |
| HGT12/orf19.7094 | Nutrient acquisition and metabolism |
| HGT8/orf19.2021 | Nutrient acquisition and metabolism |
| orf19.449 | Nutrient acquisition and metabolism |
| orf19.4905 | Nutrient acquisition and metabolism |
| orf19.5499 | Nutrient acquisition and metabolism |
| orf19.7288 | Nutrient acquisition and metabolism |
| TRP2/orf19.10080 | Nutrient acquisition and metabolism |
| RGA2/orf19.4593 | Signaling: cell polarity |
| KAR2/orf19.2013 | Signaling: unfolded protein response |
| orf19.1276 | Unknown |
| orf19.2653 | Unknown |
| orf19.2726 | Unknown |
| orf19.3335 | Unknown |
| orf19.5509 | Unknown |
| orf19.557 | Unknown |
| orf19.5782 | Unknown |
| PDR6/orf19.2094 | Unknown |
| RBT4/orf19.6202 | Unknown |