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IC50 Values (μM) of 6 – 9 on Tumor Cell Proliferation/Viability under Normoxic (Norm, 95% air) and Hypoxic (Hyp, 1% O2) Conditions Following 48 h Exposure(one experiment in triplicate).
| MCF-7 | MDA-MB-231 | T47D | PC-3 | |||||
|---|---|---|---|---|---|---|---|---|
| Norm | Hyp | Norm | Hyp | Norm | Hyp | Norm | Hyp | |
| 6 | 29 | >30 | >30 | >30 | 14 | >30 | >30 | >30 |
| 7 | 0.8 | 0.7 | 0.2 | 0.2 | 1.0 | 1.6 | 0.8 | 0.9 |
| 8 | 6.1 | 6.8 | 1.9 | 2.0 | 5.5 | 10.8 | 6.4 | 10.2 |
| 9 | 0.6 | 0.6 | 0.3 | 0.3 | 1.2 | 1.8 | 0.8 | 1.1 |
