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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Biochim Biophys Acta. 2010 Apr 11;1799(7):502–509. doi: 10.1016/j.bbagrm.2010.04.001

Figure 2. Mutagenesis of BS1-4 reveals differential functions in regulation of PKD1 promoter activity.

Figure 2

A. Schematic representation of the parental and mutant PKD1-luc promoter constructs. B. IMCD3 cells were transiently transfected with 1 μg of PKD1-luciferase promoter constructs. pSV-LacZ (0.4 μg) was co-transfected to monitor transfection efficiency. Cell lysates were harvested 24 h post-transfection and assayed for luciferase activity. Data represent mean ± S.E. of at least three experiments, * p<0.05.