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. Author manuscript; available in PMC: 2010 Jun 29.
Published in final edited form as: Biometrics. 2009 Aug 10;66(2):532–540. doi: 10.1111/j.1541-0420.2009.01302.x

Table 1.

Elicited and computed prior means of the probabilities πk,1(d), πk,2(d) for each dose pair d and outcome Yk, where k = 1 for toxicity and k = 2 for efficacy.

d1 = Dose Level of Biological Agent
d2 k 0 1 2 3 4

3 1 Elicited .85, .10 .85, .11 .85, .12 .82, .15
Computed .58, .19 .59, .18 .59, .19 .56, .22
2 Elicited .50, .33 .50, .33 .50, .33 .55, .35 .60, .38
Computed .37, .36 .39, .35 .41, .36 .41, .37
2 1 Elicited .80, .04 .80, .05 .80, .06 .80, .08
Computed .59, .15 .61, .13 .60, .14 .57, .18
2 Elicited .50, .33 .50, .33 .50, .33 .55, .35 .60, .38
Computed .37, .34 .39, .34 .40, .35 .41, .36
1 1 Elicited .70, .02 .70, .03 .70, .04 .70, .06
Computed .56, .14 .57, .13 .57, .14 .54, .17
2 Elicited .45, .25 .45, .25 .45, .25 .50, .27 .55, .30
Computed .35, .32 .37, .32 .39, .33 .39, .35