Table 1.
Elicited and computed prior means of the probabilities πk,1(d), πk,2(d) for each dose pair d and outcome Yk, where k = 1 for toxicity and k = 2 for efficacy.
| d1 = Dose Level of Biological Agent | |||||||
|---|---|---|---|---|---|---|---|
| d2 | k | 0 | 1 | 2 | 3 | 4 | |
| 3 | 1 | Elicited | – | .85, .10 | .85, .11 | .85, .12 | .82, .15 |
| Computed | – | .58, .19 | .59, .18 | .59, .19 | .56, .22 | ||
| 2 | Elicited | .50, .33 | .50, .33 | .50, .33 | .55, .35 | .60, .38 | |
| Computed | – | .37, .36 | .39, .35 | .41, .36 | .41, .37 | ||
| 2 | 1 | Elicited | – | .80, .04 | .80, .05 | .80, .06 | .80, .08 |
| Computed | – | .59, .15 | .61, .13 | .60, .14 | .57, .18 | ||
| 2 | Elicited | .50, .33 | .50, .33 | .50, .33 | .55, .35 | .60, .38 | |
| Computed | – | .37, .34 | .39, .34 | .40, .35 | .41, .36 | ||
| 1 | 1 | Elicited | – | .70, .02 | .70, .03 | .70, .04 | .70, .06 |
| Computed | – | .56, .14 | .57, .13 | .57, .14 | .54, .17 | ||
| 2 | Elicited | .45, .25 | .45, .25 | .45, .25 | .50, .27 | .55, .30 | |
| Computed | – | .35, .32 | .37, .32 | .39, .33 | .39, .35 | ||