. Author manuscript; available in PMC: 2011 Aug 1.

Published in final edited form as: Biochim Biophys Acta. 2010 Mar 15;1800(8):824–833. doi: 10.1016/j.bbagen.2010.03.004

Table 1.

	Location	Function	Size (kDa)	Crystal symmetry	Subunit	Ferroxidase center	Leader peptide
Vertebrat e	Cytoplasm	Iron storage	∼440	Octahedral	H	Yes	No
	Mitochondri a	Antioxidant			H	Yes	No
	Serum	Iron transfer/donor			L	No	No
Insect	ER	Iron transport	400-600	Tetrahedral	HCH	Yes	Yes
	Mitochondri a	Antioxidant			HCH	Yes	Yes
	Hemolymph	Iron transport/antioxidant			LCH	No	Yes