Table 3.
PCR detection of JCV DNA in archival bone marrow samples from HIV+ and HIV- patients
| HIV+ | HIV- | ||
|---|---|---|---|
| Indication for BM | no. positive/ total no. tested | p | |
| Anemia | 2/6 | 1/8 | ns |
| Splenomegaly | 1/1 | 0/1 | ns |
| Polycythemia | 0/2 | 0/2 | ns |
| Thrombocytopenia | 0/1 | ||
| MGUS | 0/2 | 0/2 | ns |
| Leukopenia | 1/1 | 0/5 | ns |
| Pancytopenia | 5/8 | 1/7 | ns |
| Lymphoma | 10/20 | 1/22 | 0.001 |
| Total | 19/41 (46%) | 3/47 (6%) | <0.01 |
BM, bone marrow biopsy; MGUS, monoclonal gammapathy of unknown significance; ns, not significant; p value indicate significance using Fischer’s Exact Test, two tailed.