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. 2010 Jun 21;11(4):383–394. doi: 10.3348/kjr.2010.11.4.383

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Copyright © 2010 The Korean Society of Radiology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 4 — Coronal T1-weighted spin-echo MR image, T2^*-weighted gradient-echo MR images, CT image, PET image, integrated PET/CT image and photomicrograph of right iliac lymph node of rabbit four weeks after VX2 tumor inoculation, and images were taken with rabbit in prone position.

A. T1-weighted spin echo image (400/12) obtained before injection of ultrasmall superparamagnetic iron oxide shows right iliac lymph node (arrow) with low signal intensity.

B. T2^*-weighted gradient-echo image (400/24, flip angle of 20°) obtained before injection of ultrasmall superparamagnetic iron oxide shows right iliac lymph node (arrow) with high signal intensity in upper portion and intermediate signal intensity in lower portion.

C. T2^*-weighted gradient-echo image (400/24, flip angle of 20°) obtained 24 hours after injection of ultrasmall superparamagnetic iron oxide shows functional tissue of right iliac lymph node with uniform low signal intensity in upper portion, and small amount of malignant tissue (arrow) with high signal intensity in lower portion.

D-F. PET and integrated PET/CT images show right iliac lymph node (arrows) without increased fluorodeoxyglucose uptake.

G. Photomicrograph of histopathologic specimen shows right iliac lymph node with 3.2 mm malignant tissue focus (arrows) (Hematoxylin & Eosin stain; ×5).