Table 2.

Correlations between the levels of memory T cell alloreactivity and the degree of MHC gene sharing between allogeneic monkey responder/stimulator pairs

TMEM	Matching at MHC locus	Number of combinations tested	p-Value
γIFN	All class I genes	111	0.0199
	Class IA	144	0.0014
	Class IB	167	0.0701
	All class II genes	154	0.0657
	Class II DR/DQ	161	0.0402
	Class II DP	186	0.1908
IL-2	All class I genes	83	0.3895
	Class IA	108	0.1729
	Class IB	103	0.8050
	All class II genes	98	0.0023
	Class II DR/DQ	105	0.0016
	Class II DP	103	0.0018

We compared the memory T-cell responses (γIFN or IL-2) in a series of responders differing from their stimulators by different MHC class I or II genes. The statistical relevance (p-values) of the correlations between the degree of gene sharing at a given locus and the level of the memory response was analyzed with a rank ANOVA using generalized estimating equation to control for the fact that certain responders had multiple representations. The p-values <0.05 (shown in bold) were considered statistically significant.