Table I.
Numbers of genes regulated by IL-12 and IFNα
| Hours | Ag-B71 vs. Naïve | IL-12+Ag-B72 vs. Ag-B7 | IFNα+Ag-B72 vs. Ag-B7 |
|---|---|---|---|
| 24 | ~3,500 | 83 | 64 |
| 48 | ~3,000 | 213 | 112 |
| 72 | ~2,300 | 730 | 610 |
1
The total number of genes with increased or decreased expression at 24, 48 or 72 hr by a fold change ≥ 1.70 in response to Ag and B7-1 relative to expression in naïve cells.
2
The number of genes that increased or decreased in expression at 24, 48 or 72 hr by ≥ 1.7-fold in response to Ag-B7 and IL-12 or IFNα relative to cells stimulated with only Ag-B7.