TABLE 2.

Ratios of GO process frequencies for genes expressed in biofilm vs nonbiofilm cells^a

GO process category	Ratio of GO process frequencies for biofilm vs nonbiofilm cells
Ribosome biogenesis and assembly	11.1
Biological process unknown	5.4
Nuclear organization and biogenesis	4.7
Amino acid and derivative metabolic process	4.5
Translation	4.3
Cytokinesis	4.1
Heterocycle metabolic process	3.6
Cell budding	3.5
Aromatic compound metabolic process	2.8
Organelle organization and biogenesis	2.8
Anatomical structure morphogenesis	2.3
DNA metabolic process	2.2
RNA metabolic process	2.2
Protein folding	2.2

^aInitially, a GO process analysis was performed on genes upregulated in both biofilm and nonbiofilm cells. The GO process categories listed here are those for which the frequency for biofilm cells was at least 2-fold higher than the frequency for nonbiofilm cells. The GO category of known biofilm formation-related genes (FLO8, MUC1, NRG1, NRG2, SNF1) was not a category for which the frequency of expression for biofilm cells was at least 2-fold higher than for nonbiofilm cells.