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. 2009 Sep 23;30(1):140–149. doi: 10.1038/jcbfm.2009.198

Figure 1.

Figure 1

Young Long Evans rats treated with MNCs have improved recovery after cortical stroke. Animals underwent CCAo/MCAo, and 24 h later either received an IA injection of autologous MNCs or saline followed by neurological testing for 30 days. (A) The cylinder test demonstrates preferential left forearm placement in animals that have undergone left CCAo/MCAo and IA saline injection at 24 h after stroke. Deficits persist up to 28 days after stroke. Animals that receive MNCs, however, at 24 h after stroke show resolution of deficits over time (P<0.05 for days 7, 14, 21, and 28; n=7 per group). (B) The corner test demonstrates preferential turning to the left in animals that have undergone left CCAo/MCAo and IA saline injection at 24 h after stroke. Deficits persist up to 28 days after stroke. Animals that receive MNCs, however, at 24 h after stroke show resolution of deficits over time (P<0.05 for days 14, 21, and 28; n=7 per group).