Table 2.
Immune response-related genes differentially expressed in Asian seabass at 24 h post challenge by bacterial lipopolysaccharides (P < 0.05)
| Cluster ID | Gene ID and description | Count-Up | Count-Down | P-value |
|---|---|---|---|---|
| Up-regulated genes | ||||
| T1 | BA1; ba1 globin (Danio rerio ) | 162 | 141 | 0.0000 |
| T2 | HBAA1; hemoglobin alpha adult-1 (Danio rerio ) | 48 | 36 | 0.0021 |
| T4 | C1QL4L; complement component 1, q subcomponent-like 4 like (Danio rerio ) | 25 | 1 | 0.0000 |
| T23 | LY6D; lymphocyte antigen 6 complex, locus D (Mus musculus ) | 9 | 0 | 0.0003 |
| T32 | IGH-1B; immunoglobulin heavy chain 1b (Homo sapiens) | 7 | 1 | 0.0091 |
| T33 | C3; complement component 3 (Mus musculus) | 8 | 0 | 0.0007 |
| T34 | SAA3; serum amyloid A 3 (Mus musculus) | 8 | 0 | 0.0007 |
| T44 | APOE; apolipoprotein E (Canis lupus) | 7 | 0 | 0.0016 |
| T45 | NCAN; neurocan (Mus musculus) | 7 | 0 | 0.0016 |
| T59 | RPS7; 40 S ribosomal protein S7 (Homo sapiens) | 5 | 1 | 0.0429 |
| T60 | RRT15; uncharacterized protein YLR162W-A (Saccharomyces cerevisiae) | 5 | 1 | 0.0429 |
| T61 | AGC1; aggrecan 1(Danio rerio) | 6 | 0 | 0.0044 |
| T82 | FGG; fibrinogen, gamma polypeptide (Rattus norvegicus) | 5 | 0 | 0.0108 |
| T83 | HDR; hematopoietic death receptor (Danio rerio) | 5 | 0 | 0.0108 |
| T84 | LCP1; lymphocyte cytosolic protein 1 (Mus musculus) | 5 | 0 | 0.0108 |
| T85 | LGMN; legumain (Danio rerio) | 5 | 0 | 0.0108 |
| T127 | APO; apolipoprotein (Lates calcarifer) | 4 | 0 | 0.0267 |
| T128 | B2M; beta-2 microglobulin (Mus musculus) | 4 | 0 | 0.0267 |
| T129 | CFL2; cofilin-2 (Gallus gallus) | 4 | 0 | 0.0267 |
| T130 | GUK1;guanylate kinase (Homo sapiens) | 4 | 0 | 0.0267 |
| T131 | mt-ND5; NADH-ubiquinone oxidoreductase chain 5 (Homo sapiens) | 4 | 0 | 0.0267 |
| T132 | TKTL2; transketolase-like protein 2 (Rattus norvegicus) | 4 | 0 | 0.0267 |
| T133 | WBP2; WW domain-binding protein 2 (Homo sapiens) | 4 | 0 | 0.0267 |
| Cg0105 | Unknown mRNA sequence | 4 | 0 | 0.0267 |
| Cg0526 | Unknown mRNA sequence | 4 | 0 | 0.0267 |
| Down-regulated genes | ||||
| T6 | HMOX1; heme oxygenase (decycling) 1 (Danio rerio ) | 1 | 19 | 0.0008 |
| T17 | EEF2L; eukaryotic translation elongation factor 2, like (Danio rerio) | 0 | 9 | 0.0134 |
| T35 | DBPHT; DNA binding protein with his-thr domain (Mus musculus) | 0 | 7 | 0.0463 |
| T36 | EEF; eukaryotic translation elongation factor (Siniperca chuatsi) | 0 | 7 | 0.0463 |
Count-Up, EST count of a given gene in the forward subtractive library; EST count in the reverse subtractive library. P < 0.05 indicates statistically significant.