Table 1. List of Seven Target Pharmaceuticals with Chemical Properties and Method Detection Level.

compound	CAS No.a	compound class	Log Kowb	water solubility (mg/L)b	method detection limitc (μg/L)
butalbital	77-26-9	barbiturate	1.87	1700	0.014
carisoprodol	78-44-4	muscle relaxant	2.36	300	0.021
diazepam	439-14-5	benzodiazepine tranquilizer	2.82	50.0	0.012
metaxalone	1665-48-1	muscle relaxant	2.60	90.7	0.011
methadone	76-99-3	opioid	3.93	48.5	0.044
oxycodone	76-42-6	opioid	0.66	4160	0.076
phendimetrazine	634-03-7	amphetamine	1.70	17300	0.021

^aThis report contains CAS Registry Numbers, which is a Registered Trademark of the American Chemical Society. CAS recommends the verification of the CASRNs through CAS Client Services.

^bChemical properties from online database http://www.syrres.com/esc/physdemo.htm (viewed January 2008).

^cMethod detection limits were determined from 10 reagent water samples fortified at 0.05 μg/L and 7 reagent water samples fortified at 0.20 μg/L.