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Structures of Fn (top) and FnBPA (bottom) drawn to scale. Highlighted are regions on Fn (N-terminal Fn-I and Fn-II domains) and FnBP (A, B1, B2, Du, C, D1-D4) that are important in binding. Fn is approximately 2000 amino acids or 800 nm in length, and FnBPA is approximately 1000 amino acids or 400 nm in length.
