Table 3.
CpG Targets with Differential Methylation (Δβ ≥0.17) between H&E or Immunohistochemically Stained Tumor Cells
| Target ID* | β (HE) | β (IHC) | Δβ | P value |
|---|---|---|---|---|
| p16_seq_47_S85_F | 0.509 | 0.833 | 0.324 | 0.002 |
| EGR4_E70_F | 0.343 | 0.633 | 0.290 | 0.000 |
| NRG1_E74_F | 0.646 | 0.455 | 0.191 | 0.044 |
| VAMP8_E7_F | 0.239 | 0.411 | 0.172 | 0.015 |
*
Gene symbols are contained within the Target ID before the first underscore. β (HE) indicates mean beta value of all five cases of PMLBCL stained with H&E; β (IHC), mean beta value of all five cases of PMLBCL stained with IHC (CD20); Δβ, differential methylation between β (HE) and β (IHC). P value calculation: see Materials and Methods.