Table 3.

Conventional Cytogenetic and D-FISH Results Using a Homebrew MLL/MLLT3 Probe for 20 Patients with t (9;11) (p22;q23)

		Conventional cytogenetic analysis	FISH analysis*
Patient no.	Age (years)	Karyotype	Abnormal nuclei (%)	Interphase signal pattern
46	7 M	43-46,XX,t (9;11) (p22;q23),dic(9;13) (p22;q12),der(11)t (9;11)(p22;q23), del(12) (p11.2p13),del(13) (q12q14) [cp18]/46,XX[2]	87.4	1R2G1F
47	23 M	48,XX,der(9)t (9;11) (p24;p11.2),der(9)t (9;11) (p22;q23),+10, der(11)t (9;11) (p24;p11.2),t (9;11) (p22;q23),+19[7]/49,idem,+8[2]/46,XX[11]	10.6	1R1G2F
48	11	46,X,t (X;Y) (q28;q11.2)?c[3]/46,idem,t (9;11) (p22;q23) [17]	85.8	1R1G2F
49	15	46,XY,t (9;11) (p22;q23) [11]/46,idem,der(?)t (1;?) (q23;?) [2]/ 47,idem,+8[2]/48,idem,+8,+19[5]	93.4	1R1G2F
50	18	46,XX,t (9;11) (p22;q23) [19]/47,XX,+9,t (9;11) (p22;q23) [1]	82.2	1R1G2F
51	30	46,XY,t (9;11) (p22;q23) [20]	93.6	1R1G2F
52	31	48,XX,+4,t (9;11) (p22;q23),+12,t (17;18) (p10;q10)?c[cp20]	88.4	1R1G2F
53	39	46,XY,t (9;11) (p22;q23) [20]	90.4	1R1G2F
54	41	48,XX,+8,t (9;11) (p22;q23),+19[20]	97	1R1G2F
55	42	47,XY,t (9;11) (p22;q23),+21[3]/46,X,-Y,t (9;11),+21[16]/46,XY[1]	95	1R1G2F
56	46	46,XY,t (9;11) (p22;q23) [20]	74	1R1G2F
57	48	46,XX,t (9;11) (p22;q23) [20]	89	1R1G2F
58	54	46,XX,t (9;11) (p22;q23) [20]	91.6	1R1G2F
59	58	50,XX,+4,+8,t (9;11) (p22;q23),+12,+20[20]	93.2	1R1G2F
60	60	46,XX,t (9;11) (p22;q23) [20]	92.4	1R1G2F
61	61	46,XY,t (9;11) (p22;q23) [20]	92.6	1R1G2F
62	62	46,XY,t (9;11) (p22;q23) [20]	95.2	1R1G2F
63	70	46,XX,t (9;11) (p22;q23) [19]/46,XX[1]	85.2	1R1G2F
64	76	46,XX,t (9;11) (p22;q23) [23]	92.6	1R1G2F
65	77	46,XX,t (9;11) (p22;q23) [20]	85.6	1R1G2F

F, fusion (yellow); G, green; M, months; R, red.

^*A total of 500 interphase nuclei were analyzed by two technologists (250 nuclei each).