Table 2.

Performance of Different Techniques for the Selection of Patients with MLH1-Negative Tumors for Genetic Testing of MLH1 Germline Mutation

	Germline mutation (n = 10)		No germline mutation (n = 63)
Techniques	N	%	N	%	Odds ratio	P
MethyLight
Not methylated	10	100	16	25.4	1.6 (1.2–2.2)	<0.001
Methylated	0	0	47	74.6
MS-MLPA
Not methylated	10	100	14	22.2	1.7 (1.2–2.4)	<0.001
Methylated	0	0	49	77.8
BRAF mutation
Not mutated	10	100	38	60.3	1.3 (1.1–1.5)	<0.05
Mutated	0	0	25	39.7