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. 2010 Jun 10;4:16. doi: 10.3389/fncel.2010.00016

Figure 2.

Figure 2

Quantification of changes in expression levels of CB1 (A,B) and VGAT (C,D) in human visual cortex across the lifespan. The graphs follow the same conventions as described in Figure 1. CB1 levels are high in infants (<1 year) then fall into young children (1–2 years) before rising again in pre-teens (5–11 years) and falling again in teens (12–20 years) and leveling off (Kruskal–Wallis, p < 0.0001) (A,B). For VGAT 2 bands were quantified (arrows at 50 and 57 kDa). VGAT levels are highest in infants (<1 year) then gradually fall into children (3–4 years) before rising again into pre-teens (5–11 years) then falling into adults (21–55 years) before finally rising again in older adults (>55 years) (Kruskal–Wallis, p < 0.005) (C,D). The lines above the histograms identify the groups that were significantly different (Tukey's post hoc HSD, *p < 0.05, **p < 0.02, ***p < 0.001) (● average expression for each case; Inline graphic all runs; dotted line is the weighted average).