Figure 3.

Moving towards resting state abnormalities as a diagnostic marker in Alzheimers: Using parameters derived from resting state functional connectivity and choosing an appropriate threshold one can show good segregation between patients with Alzheimers disease (AD) and healthy elderly (A). Instead of picking just one threshold, receiver operating characteristic (ROC) curves can show the sensitivity and specificity at several different thresholds (B,C). Below each figure are the sensitivity and specificity values obtained by choosing the ideal threshold to segregate the populations in each study. Adapted with permission from (Li et al., 2002; Greicius et al., 2004; Supekar et al., 2008).