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. Author manuscript; available in PMC: 2010 Jun 29.
Published in final edited form as: J Med Primatol. 2009 Apr;38(2):137–144. doi: 10.1111/j.1600-0684.2008.00321.x

Table 1.

Neoplasia in the chimpanzee.

Case # Location Diagnosis Sex Age (Years) at
Diagnosis		 Malignant or
Benign		 Commentsa Reference
Urogenital System
1 Uterus Leiomyoma F 31 B
2 Uterus Leiomyoma F 44 B
3 Uterus Leiomyoma F 40 B
4 Uterus Leiomyoma F 40 B
5 Uterus Leiomyoma F 31 B
6 Uterus Leiomyoma F 45 B
7 Uterus Leiomyoma F 32 B
8 Uterus Leiomyoma F 41 B
9 Uterus Leiomyoma F 36 B
10 Uterus Leiomyoma F 37 B
11 Uterus Leiomyoma F 29 B
12 Uterus Leiomyoma F 38 B
13 Uterus Leiomyoma F 41 B
14 Uterus Leiomyoma F 28 B
15 Uterus Leiomyoma F 42 B
16 Uterus Leiomyoma F 44 B
17 Uterus Leiomyoma F 55 B
18 Uterus Leiomyoma F 19 B 43
19 Uterus Leiomyoma F 23 B 36
20 Uterus Leiomyoma F 25 B 41
21 Uterus Leiomyoma F 40 B
22 Uterus Leiomyoma F 26 B
23 Uterus Leiomyoma F 39 B
24 Uterus Leiomyoma F 47 B
25b Uterus Leiomyoma F 42 B Experimental HBV
infection
26 Uterus Leiomyoma F 22 B 37
27 Cervix, vagina Leiomyoma F 45 B
28 Oviduct Leiomyoma F 31 B
29 Kidney Carcinoma F 17 M 12
30 Unk Leiomyoma F 44 B 39
31 Unk Leiomyoma F 44 B 39
32 Unk Leiomyoma F 44 B 39
33 Unk Leiomyoma F 47 B 39
34 Unk Leiomyoma F 23 B
35 Vagina Leiomyoma F 31 B
36 Vagina Leiomyoma F 26 B
37 Vagina Angiofibroma F 47 B
38 Uterus Adenocarcinoma in
situ, endothelium		 F 23 M Adenomatous
hyperplasia of
endometrium		 17
39 Uterus Carcinoma F Unkb,c M 16
40 Uterus Endometrial
stromal		 F 25 B 41
41 Uterus Partial hydatid mole F 30 B Mole in placenta of
stillborn		 9
42 Uterus Polyp F 40 B 4
43 Ovary Fibrothecoma F 38 B 11
44 Ovary Fibrothecoma F 48 B 11
45 Ovary Fibrothecoma F 48 B 11
46 Ovary Granulosa cell
tumor		 F 31 B
47 Ovary Granulosa cell
tumor		 F 32 B
48 Ovary Teratoma F 22 B
49 Ovary Brenner tumor,
right ovary		 F 32 B
50 Ovary Sertoli-Leydig cell
tumor		 F 38 B 11
Integumentary System
51 Skin Papilloma F 4 B 35
52 Skin Papilloma F 1 B
53 Skin Papilloma F 25 B
54 Skin Papilloma F 27 B
55 Skin Papilloma Unkb Unkb B 17
56 Skin Papilloma Unkb Unkb B Pan paniscus 40
57 Unk Papilloma M 7 B 10
58 Unk Papilloma M Adult B 10
59 Unk Papilloma M Unkb B 10
60 Unk Papilloma Unkb Unkb B 10
61 Subcutis Lipoma F 29 B 17
62 Subcutis Lipoma F 31 B
63 Subcutis Lipoma F 35 B
64 Subcutis Lipoma F 44 B 17
65 Subcutis Lipoma F 28 B
66 Unk Lipoma Unkb Unkb B 17
67 Unk Basosquamous cell
carcinoma		 F 39 M
68 Subcutis Nevus lipomatosus
cutaneous
superficialis		 M 32 B 16
69b Subcutis Osteosarcoma Unk Unk M Transplant of human
osteosarcoma
nonproducer cells
infected with baboon
endogenous virus		 28
Endocrine System
70 Pituitary Adenoma F 44 B
71 Pituitary Adenoma F 32 B
72 Pituitary Adenoma M 46 B
73 Pituitary Adenoma F 22 B
74 Adrenal Cortical adenoma M 34 B
75 Adrenal Cortical adenoma F 8 B 17
76 Adrenal Neurofibroma M 28 B
77 Thyroid Follicular cell
Adenoma		 F 31 B
78 Thyroid Follicular cell
adenoma		 M 28 B
79 Thyroid Thyroid carcinoma M 34 M
80 Pancreas Islet cell adenoma M 16 B 17
81 Pancreas Islet cell
(adenomatosis)		 F 47 B 17
82 Kidney Ectopic
adrenalcortical
carcinoma		 F 47 B 17
Alimentary System
83 Liver Hepatocellular
carcinoma		 M 16 M
84 Liver Hepatocellular
carcinoma		 M 34 M
85 Liver Hepatocellular
carcinoma		 F 28 B
86 Liver Hepatocellular
carcinoma		 M 16 M 27
87b Liver Hepatocellular
carcinoma		 F 12 M Chronic Schistosoma
mansoni infection;
HBV/HCV		 1
88b Liver Hepatocellular
carcinoma		 M 14 M Experimental infection:
NANBH human plasma
(w/chronic HCV)		 24
89b Liver Hepatocellular
carcinoma		 M 7 M Experimental HBV
infection; delta
hepatitis; no NANBH
exposure		 24
90b Liver Hepatocellular
carcinoma		 M 28 M Experimental HBV
91b Liver Carcinoma, poorly
differentiated		 F 42 M Experimental HBV
infection
92b Liver Hepatocellular
adenoma		 M 17 B Experimental infection:
NANBH human
plasma; HBV/HCV +;
tumor diagnosis
questionable -
described as resembling
hepatocellular
carcinoma		 24
93b Liver Myelolipoma M 21 B Experimental
HCV/HIV infection		 27
94 Stomach Gastrointestinal
stromal tumor		 M 22 B 32
95 Colon Gastrointestinal
stromal tumor		 M 33 B
96b Rectum Gastrointestinal
stromal tumor		 F 42 B Experimental HBV
infection
97 Gall bladder Adenoma F 37 B 39
98 Duodenum Adenomatosis benign
glandular tumor of
the Brunner's glands		 F 44 B 17
99 Jejunum Polyposis M 40 B 10
100 Rectum Leiomyosarcoma F 26 M
101 Parotid
salivary
gland		 Adenocarcinoma M 40 M
Cardiovascular System
102 Kidney Hemangioma M 31 B
103 Kidney Hemangioma M 33 B
104 Spleen Hemangioma M 29 B
105 Subcutis Hemangioma F 52 Days B 20
106b Unk Endothelioma Unk Unk Unk 22
107 Lymphatics Angioendothelioma
(Dabska-like tumor)		 M 4 B Synonyms: malignant
endovascular papillary
angioendo-thelioma,
papillary
intralymphatic
angioendothelioma		 2
Musculoskeletal System
108 Scapula Sarcoma F Unkb M 22
109 Unk Sarcoma M 15 M 18
110 Maxilla Odontoma Unkb Unkb B 10
Respiratory System
111 Nasal cavity Cartilaginous
fibromyxoma (nasal
polyp)		 M 11 B Tumor near molar
projection of palantine
bone		 26
112 Nose Fibromyxomatous
polyposis		 F 10 B Polyp obstructed
almost entire upper
respiratory tract		 14
113 Nasopharynx Carcinoma F 10 M Tumor had
intracranial/skull cavity
extension		 3
Hematopoietic System
114 Abdominal
cavity		 Anaplastic large cell
lymphoma (T-cell
phenotype)		 M 35 M Negative for
retroviruses, no other
virus isolated		 6
115b Bone
marrow		 Erythroleukemia M 1 M Experimental infection:
bovine C-type virus		 4
116b Bone
marrow		 Erythroleukemia M 1 M Experimental infection:
bovine C-type		 4
Central Nervous System
117b Brain Brain tumor of
unknown type		 Unk Unk Unk 17
a

HBV, hepatitis B virus; HCV, hepatitis C virus; NANBH, non-A, non-B hepatitis virus; HIV, human immunodeficiency virus

b

Not included in statistical analysis

c

Unk, unknown