Table 1.
Polymer | Drug loading (%) | Surfactant | Size (nm) | PDI | ZP (mV) | EE (%) |
---|---|---|---|---|---|---|
PLGA-TPGS | 2.5 | No | 207.15 ± 8. 46 | 0.321 ± 0.03 | 58.87 ± 3.25 | |
PLGA-TPGS | 5 | No | 223.92 ± 6.27 | 0.372 ± 0.04 | 52.58 ± 2.94 | |
PLGA-TPGS | 10 | No | 244.71 ± 6.65 | 0.415 ± 0.02 | −24.09 ± 1.45 | 48.35 ± 5.73 |
PLGA-TPGS | 10 | 0.03% TPGS | 265.43 ± 6.52 | 0.364 ± 0.03 | −18.03 ± 1.89 | 99.31 ± 0.56 |
PLGA-TPGS | 10 | 0.06% TPGS | 290.25 ± 7.64 | 0.485 ± 0.01 | −15.22 ± 2.12 | 85.85 ± 3.14 |
PLGA | 10 | 0.03% TPGS | 233.83 ± 9.62 | 0.293 ± 0.03 | −32.10 ± 0.65 | 75.63 ± 3.42 |
* PDI Polydispersity Index, EE Drug encapsulation efficiency, n = 3