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Mph1, the Shu complex, and Mms2 have nonoverlapping functions in DNA repair. Wild-type (WT) and mutant cell cultures were diluted and spotted onto YPD plates with or without the indicated concentration of MMS. mph1Δ enhances the MMS sensitivity of shu1Δ (A), csm2Δ (B), and mms2Δ (C) cells. shu1Δ enhances the MMS sensitivity of mms2Δ cells (D).
