Figure 6.

Comparison of the growth inhibitory effects of RGD-M-LCL and RGD-LCL on Bcap-37 cells. Bcap-37 cells were treated with various concentrations of RGD-LCL and RGD-M-LCL (equivalent to the same concentration of RGD-LCL) for 48h, and were again plotted as the ratio to the control group. In the cells treated with 0.3125 mg/mL or 0.625 mg/mL of RGD-LCL, the inhibitory effect of liposomes on Bcap-37 cells was minimal, while the RGD-M-LCL equivalent to the same dose of RGD-LCL strongly inhibited the growth of the cancer cells. However, in the cells treated with 1.25 mg/mL or 2.5 mg/mL of RGD-LCL, RGD-LCL itself was moderately cytotoxic to the Bcap-37 cells. *P < 0.01 when compared to the equivalent RGD-LCL group.