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. 2010 Jun 14;7(4):197–208. doi: 10.7150/ijms.7.197

Figure 8.

Figure 8

Representative results of apoptosis in Bcap-37 cells in different treatment groups. Bcap-37 cells were treated with different treatment of culture medium, free matrine, RGD-LCL or RGD-M-LCL for 24 h, then were stained with Annexin-V-FITC and PI, and assayed by flow cytometry. Compared with the control group, matrine at 0.03125 mg/mL had no effect on the apoptosis of cancer cells. However, RGD-LCL at 0.625 mg/mL could induce apoptosis in the Bcap-37 cells. Furthermore, treatment with RGD-M-LCL led to apoptosis in 37.1% of the cells, which was, significantly higher than the extent of apoptosis seen in the control, matrine and RGD-LCL groups. (A) control group, (B) matrine at 0.03125 mg/mL, (C) RGD-LCL at 0.625 mg/mL, (D) RGD-M-LCL equivalent to these concentration of matrine and RGD-LCL.