Table 3.
DTI Indices in MCI Patients and Controls1
| MCI (N=14) | Controls (N=9) | P value | |
|---|---|---|---|
| Temporal Region: | |||
| Average FA | .28 (.06) | .34 (.06) | .01 |
| Left Hemisphere | .27 (.07) | .34 (.07) | .04 |
| Right Hemisphere | .28 (.06) | .34 (.07) | .04 |
| Average ADC | 928.0 (80.6) | 861.3 (30.9) | .03 |
| Left Hemisphere | 927.4 (77.9) | 858.3 (43.3) | .02 |
| Right Hemisphere | 928.7 (112.2) | 864.2 (45.2) | .12 |
| Prefrontal Region: | |||
| Average FA | .30 (.03) | .29 (.03) | .49 |
| Left Hemisphere | .30 (.03) | .29 (.02) | .35 |
| Right Hemisphere | .29 (.05) | .28 (.04) | .66 |
| Average ADC | 885.4 (78.0) | 859.5 (58.0) | .40 |
| Left Hemisphere | 873.1 (82.1) | 863.0 (69.0) | .75 |
| Right Hemisphere | 897.6 (97.9) | 856.4 (55.3) | .27 |
| Whole Brain: | |||
| FA | .26 (.03) | .26 (.02) | .77 |
| ADC | 1223.1 (113.1) | 1139.3 (106.6) | .09 |
1
FA=Fractional Anisotrophy; ADC=Apparent Diffusion Coefficient. Higher values of FA and lower values of ADC signify greater WM integrity.