Table 4.
Quercetin and isorhamnetin levels in tissues of xenograft mice treated with 1% and 0.2% quercetin for 6 weeksa
| 0.2% quercetin diet | 1% quercetin diet | |||
|---|---|---|---|---|
| Q | I | Q (aglycone) | I (aglycone) | |
| nmol/g wet tissue | ||||
| Liver | 0.65 ± 0.13 | 0.37 ± 0.09 | 5.12 ± 1.24 (5.45 ± 1.28) | 3.69 ± 0.88 (3.56 ± 0.92) |
| Lung | 0.67 ± 0.18 | NDb | 3.04 ± 0.41 (2.17 ± 0.45) | 3.44 ± 0.51 (1.36 ± 0.38) |
| Pancreas | 1.16 ± 0.47 | 0.69 ± 0.21 | 4.72 ± 1.60 (3.98 ± 1.48) | 3.46 ± 0.32 (3.14 ± 1.27) |
| Tumor | 0.51 ± 0.12c | 0.30 ± 0.09c | 2.64 ± 1.15d (1.69e) | 2.16 ± 0.35d (1.61e) |
a
Values are mean ± SEM.
b
ND, not detected.
c
n=5.
d
n=6.
e
n=2.
Q, quercetin; I, isorhamnetin.