TABLE 1. Demographic Characteristics of Subjects

	Normal Comparison Subjects							Subjects With Schizophrenia								Cortical Area
Pair	Sex	Race	Age (years)	Postmortem Interval (hours)	RNA Integritya	Storage Time (months)b	Cause of Death	Sex	Race	Age (years)	Postmortem Interval (hours)	RNA Integritya	Storage Time (months)b	Cause of Death	DSM-IV Diagnosis	Area 9	Area 24	Area 4	Area 17
1	Male	Black	41	22.1	9.0	116	Atherosclerotic coronary vascular disease	Male	White	40	29.1	8.4	126	Accidental asphyxiation	Chronic undifferentiated schizophrenia	√	√	√	√
2	Male	Black	20	14.0	8.4	127	Gun shot wound to chest	Male	Black	27	16.5	7.4	123	Heat stroke	Schizoaffective disorderc, d	√	√	√	√
3	Male	White	65	21.2	9.0	110	Atherosclerotic coronary vascular disease	Male	White	63	18.3	8.0	120	Atherosclerotic coronary vascular disease	Chronic undifferentiated schizophreniac, e	√	√	√	√
4	Male	White	39	19.3	8.6	113	Hypoplastic coronary artery disease	Male	White	46	28.1	7.9	118	Accidental combined drug overdose	Chronic paranoid schizophreniac, d, f, g	√	√	√	√
5	Male	White	56	14.5	8.1	103	Hypoplastic coronary artery disease	Male	White	58	18.9	7.4	111	Right middle cerebral artery infarction	Chronic undifferentiated schizophreniah	√	√	√	√
6	Male	Black	19	7.0	9.2	96	Trauma	Male	White	25	5.0	9.3	77	Suicide by drug overdose	Schizoaffective disorderc, d, f, h, i	√	√	√	√
7	Female	Black	55	11.3	9.6	118	Atherosclerotic coronary vascular disease	Female	White	48	3.7	9.3	127	Intracerebral hemmorrhage	Chronic disorganized schizophreniaf	√			√
8	Male	White	42	26.1	8.7	100	Atherosclerotic coronary vascular disease	Male	White	50	40.5	8.1	125	Suicide by combined drug overdose	Schizoaffective disorderd, j	√	√	√	√
9	Male	White	54	8.0	9.1	72	Cardiac tamponade	Male	Black	52	8.0	7.7	87	Peritonitis	Schizoaffective disorderj	√	√
10	Female	White	73	19.7	7.7	10	Anaphylactic reaction	Female	White	71	23.8	7.0	60	Atherosclerotic coronary vascular disease	Chronic undifferentiated schizophrenia	√	√	√
11	Male	White	48	16.6	8.9	71	Atherosclerotic coronary vascular disease	Male	White	47	15.7	8.2	57	Atherosclerotic coronary vascular disease	Continuous disorganized schizophreniad, i, j	√	√	√	√
12	Male	White	40	15.8	8.4	95	Atherosclerotic coronary vascular disease	Male	White	44	8.3	8.1	56	Myocarditis	Disorganized schizophreniad	√	√	√

^aAssessed as RNA integrity number and measured on the Agilent 2100 bioanalyzer (Agilent Technologies, Santa Clara, Calif.).

^bTissue stored at −80°C.

^cTaking benzodiazepines at time of death.

^dTaking valproic acid at time of death.

^eAlcohol abuse in remission at time of death.

^fAlcohol dependence current at time of death.

^gOther substance abuse current at time of death.

^hNot taking antipsychotic medication at time of death.

ⁱOther substance abuse in remission at time of death.

^jAlcohol dependence in remission at time of death.