Table 2.
Baseline and exercise test characteristics according to Bruce stage 2 exercise BP groups
| Bruce stage 2 exercise systolic BP, mmHg | |||||
|---|---|---|---|---|---|
| ≤146 | 147–160 | 161–180 | >180 | P, trend | |
| Demographic and clinical * | |||||
| Age, years | 41.0 (8.5) | 42.6 (8.8) | 44.9 (9.8) | 49.8 (11.0) | <0.001 |
| Hypertension | 6.3 | 14.8 | 27.6 | 50.3 | <0.001 |
| Current smoker | 38.6 | 35.2 | 38.1 | 34.1 | 0.03 |
| Diabetes | 1.0 | 2.0 | 3.1 | 6.1 | <0.001 |
| Family history of CHD <60years┼ | 19.5 | 17.3 | 18.2 | 15.3 | 0.03 |
| Total cholesterol, mg/dL | 211 (49) | 218 (44) | 225 (44) | 228 (45) | <0.001 |
| LDL cholesterol, mg/dL | 137 (40) | 143 (41) | 149 (41) | 150 (41) | <0.001 |
| HDL cholesterol, mg/dL | 52 (15) | 50 (15) | 49 (15) | 49 (16) | <0.001 |
| Triglycerides, mg/dL | 130 (217) | 148 (122) | 167 (144) | 184 (178) | <0.001 |
| Body mass index, kg/m2 | 24.3 (3.7) | 25.7 (3.7) | 26.6 (4.1) | 27.2 (4.1) | <0.001 |
| Regular exerciseǂ | 24.4 | 25.9 | 25.0 | 21.7 | 0.07 |
| Exercise test | |||||
| Rest BP | |||||
| Systolic, mmHg | 111.3 (11.4) | 118.7 (12.0) | 125.2 (13.3) | 135.9 (16.9) | <0.001 |
| Diastolic, mmHg | 73.3 (9.1) | 77.9 (9.4) | 81.3 (9.5) | 85.2 (10.2) | <0.001 |
| Bruce stage 2 BP | |||||
| Systolic, mmHg | 134.4 (9.1) | 154.8 (4.5) | 171.9 (6.0) | 200.0 (15.7) | --- |
| Diastolic, mmHg | 74.8 (10.6) | 80.0 (11.0) | 83.7 (13.0) | 91.4 (16.0) | <0.001 |
| Maximum BP during exercise | |||||
| Systolic, mmHg | 155.1 (17.0) | 171.2 (14.2) | 187.0 (15.2) | 209.9 (18.5) | <0.001 |
| Diastolic, mmHg | 79.4 (9.6) | 84.5 (10.2) | 88.7 (12.0) | 96.6 (15.1) | <0.001 |
| Proportion achieving target HR | 75.7 | 77.0 | 76.2 | 67.1 | <0.001 |
| Exercise capacity, METs | 10.0 (2.3) | 9.9 (2.3) | 9.6 (2.2) | 8.8 (2.1) | <0.001 |
| Bruce stage 2 exercise diastolic BP, mmHg | |||||
|---|---|---|---|---|---|
| ≤73 | 74–80 | 81–90 | >90 | P, trend | |
| Demographic and clinical * | |||||
| Age, years | 42.8 (10.4) | 43.2 (9.3) | 45.0 (9.7) | 47.5 (10.4) | <0.001 |
| Hypertension | 12.1 | 15.8 | 26.5 | 47.1 | <0.001 |
| Current smoker | 38.1 | 39.4 | 33.8 | 33.9 | 0.001 |
| Diabetes | 1.7 | 1.9 | 3.7 | 4.6 | <0.001 |
| Family history of CHD <60years┼ | 17.4 | 18.2 | 17.2 | 17.9 | 0.89 |
| Total cholesterol, mg/dL | 214 (43) | 219 (43) | 224 (47) | 228 (50) | <0.001 |
| LDL cholesterol, mg/dL | 140 (39) | 144 (41) | 146 (43) | 150 (41) | <0.001 |
| HDL cholesterol, mg/dL | 52 (15) | 50 (16) | 50 (15) | 48 (16) | <0.001 |
| Triglycerides, mg/dL | 135 (106) | 146 (114) | 162 (148) | 191 (284) | <0.001 |
| Body mass index, kg/m2 | 24.8 (3.6) | 25.6 (4.0) | 26.4 (4.0) | 27.2 (4.3) | <0.001 |
| Regular exerciseǂ | 21.8 | 26.7 | 26.1 | 21.9 | 0.001 |
| Exercise test | |||||
| Rest BP | |||||
| Systolic, mmHg | 116.4 (14.2) | 118.8 (14.3) | 124.0 (14.7) | 132.7 (17.0) | <0.001 |
| Diastolic, mmHg | 75.0 (9.3) | 76.7 (9.4) | 80.8 (9.2) | 86.2 (10.7) | <0.001 |
| Bruce stage 2 BP | |||||
| Systolic, mmHg | 153.3 (22.8) | 156.7 (21.6) | 166.9 (22.1) | 184.9 (23.7) | <0.001 |
| Diastolic, mmHg | 65.0 (7.5) | 78.5 (2.2) | 87.4 (2.9) | 102.0 (8.2) | --- |
| Maximum BP during exercise | |||||
| Systolic, mmHg | 169.6 (23.8) | 173.5 (23.1) | 182.2 (22.6) | 198.6 (23.8) | <0.001 |
| Diastolic, mmHg | 73.6 (8.2) | 82.6 (5.6) | 91.2 (6.1) | 105.0 (9.2) | <0.001 |
| Proportion achieving target HR | 74.6 | 75.7 | 74.9 | 71.4 | 0.06 |
| Exercise capacity, METs | 9.6 (2.3) | 9.9 (2.2) | 9.6 (2.2) | 9.2 (2.2) | <0.001 |
Values shown are mean (SD) or percentage
*
See text for abbreviations.
┼
Family history: premature coronary heart disease in a parent or sibling.
ǂ
Regular exercise: self-reported participation in regular strenuous activity or hard labor.