Figure 3.
Immunohistologic features of nodal marginal zone lymphoma
The first row depicts a NMZL case example in which (A) the neoplastic CD20-positive B-cells co-express CD43 (strong and diffuse, B) and CD23 (weak and focal, C). The second row shows different patterns of follicular dendritic cell meshworks highlighted by the stain for CD21 (D), with follicular colonization (E), and intrafollicular nests of FDC cells. The third row shows the variable staining pattern for Ki-67 (G), increased labeling of Ki-67 in found within residual germinal centers (H), whereas low to moderate numbers of Ki-67-postive cells are highlighted in the interfollicular areas where the Ki-67 stain appears to preferentially highlight admixed large transformed cells (I).
