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. 2010 Mar 24;7(50):1341–1354. doi: 10.1098/rsif.2010.0063

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© 2010 The Royal Society

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Figure 3. — The alignment of yeast2 and human1 PPI networks. An edge between two nodes means that an interaction exists in both species between the corresponding protein pairs. Thus, the displayed networks appear, in their entirety, in the PPI networks of both species. (a) The largest common connected subgraph (CCS) consisting of 900 interactions amongst 267 proteins. (b) The second largest CCS consisting of 286 interactions amongst 52 proteins; each node contains a label denoting a pair of yeast and human proteins that are aligned.