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. 2010 Jun 30;5(6):e11402. doi: 10.1371/journal.pone.0011402

Figure 4. Surface expression of MHC class II DR.

Figure 4

4A Peripheral blood mononuclear cells derived from sheep homozygous for i; DRA*0201/DRB1*0901, ii; DRA*0102/0501 and iii; DRA*0101/0301 using DRα chain specific monoclonal antibody VPM 54. Horizontal axis FSC, forward scatter (cell size), vertical axis FL1, fluorescence channel 1. The percentage of positive events above the cut-off set based of the unlabelled population is shown in the top right. 4B Peripheral blood mononuclear cells derived from sheep homozygous for i; DRA*0201/DRB1*0901, ii; DRA*0102/0501 and iii; DRA*0101/0301 using DRβ chain specific monoclonal antibody VPM 57. 4C Peripheral blood mononuclear cells derived from sheep homozygous for i; DRA*0201/DRB1*0901, ii; DRA*0102/0501 and iii; DRA*0101/0301 using DQα chain specific monoclonal antibody VPM 36. 4D COS-7 cells transfected with haplotype matched and mismatched combinations of DRA/B genes. i; DRA*0201 and DRB1*0901, ii; DRA*0201 and 0501, iii; DRA*0201 and 0301 and iv; DRA*0201 only.