Figure 6.

Conductance correlations in model solution spaces. Each triangular panel shows pairwise conductance correlations found in a subset of model neurons from a model neuron set constructed by systematic parameter space exploration (Prinz et al. 2003). Membrane conductances include a sodium conductance (Na), transient and slow calcium conductances (CaT and CaS), transient, delayed rectifier and calcium-dependent potassium conductances (A, Kd and KCa) and a leak conductance. ‘Parent’ populations (bottom row) contain bursting model neurons that match one output measure range, as indicated. Slow wave refers to the slow voltage oscillation underlying the spikes. Duty cycle is defined as the ratio between burst duration and burst period. ‘Child’ populations (upper rows) are obtained by combining their parents' output measure ranges as indicated by arrows. Within each triangular panel, ‘plus ’ indicates a positive pairwise conductance correlation, ‘minus’ indicates a negative pairwise conductance correlation and grey shading indicates that a pairwise correlation was present in one of the parents. Adapted from Hudson & Prinz (submitted).