Table 2.
General characteristics of cases and controls: A Mayo Clinic case-control study of lung cancer, 1998–2007
| Characteristics | Cases (574) N(%) |
Controls (679) N(%) |
p a |
|---|---|---|---|
| Race | |||
| Caucasian | 574 (100) | 679 (100) | |
| Gender | 0.327 | ||
| Female | 300(52.3) | 336(49.5) | |
| Male | 274(47.7) | 343(50.5) | |
| Age(years) | 0.771 | ||
| <=50 | 143(24.9) | 159(23.4) | |
| 50–79 | 360(62.7) | 439(64.7) | |
| >79 | 71(12.4) | 81(11.9) | |
| Cigarette smoking | <0.001 | ||
| Never | 202(35.2) | 304(44.8) | |
| Ever | 372(64.8) | 375(55.2) | |
| Second hand smoking | <0.001 | ||
| No | 76(13.2) | 134(19.7) | |
| Yes | 498(86.8) | 545(80.3) | |
| History of COPD | <0.0001 | ||
| No | 382(66.6) | 659(97.1) | |
| Yes | 192(33.4) | 20(2.9) | |
| Family history of lung cancer | <0.0001 | ||
| No | 503(87.6) | 656(96.6) | |
| Yes | 71(12.4) | 23(3.4) | |
| Histological types | |||
| Adenocarcinoma | 266(46.3) | – | |
| Squamous cell carcinoma | 115(20.0) | – | |
| Non-small cell carcinoma | 45(7.8) | – | |
| Small-cell carcinoma | 17(3.0) | – | |
| Large-cell carcinoma | 11(1.9) | – | |
| Bronchoalveolar carcinoma | 26(4.5) | – | |
| Carcinoid carcinoma | 40(7.0) | – | |
| Mixed histology/other | 54(9.5) | – | |
| Tumor stages | |||
| I +II | 255(44.4%) | – | |
| III+IV | 319(55.6%) | – |
a
Pearson’s chi-square test.