Fig. 1.

Mp burden is increased in allergic W/W^v mice. Mice were challenged with OVA or saline prior to infection with 10⁸ CFU Mp/mouse. The left lobe of the lung was collected 7 days after infection and homogenized for Mp culture. (A) Mp burden in allergic W/W^v mice is dose-dependent; n = 9-10 and data presented was collected from one replicate. (B) Lung Mp burden is increased in allergic W/W^v mice compared to littermate controls (+/+) and in non-allergic W/W^v mice compared to controls; n = 17-18 and data are pooled from the results of two independent replicates. Mp burden is presented as the number of live colonies (log₁₀ of CFU ± SEM). Comparison between groups was performed using a Student's t-test, * p < 0.05.