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Changes in signal transduction pathways induced by MSC. Protein cell lysates were prepared from BV173 cell cultures after treatment with 1 or 5 μM imatinib for 72 h, in the presence or absence or MSC. Protein expression of Bcl-XL, Bax, CXCR4, caspase-3 and Akt was measured by western blot analysis (A). Densitometric data (B) are expressed as mean fold change from three independent experiments. All densitometric data were normalized for total Akt signals.
